Division of Biophysical ChemistryDepartment of Pharmaceutical Health Care,
Faculty of Pharmaceutical Sciences,
Himeji Dokkyo University

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Prof. Okamura delivered an Invited Lecture at the 36th International Conference on Solution Chemistry, Xining, China. Dr. Aki was also selected as one of the Top 5 Poster Winners (Excellent). (August 23, 2019)

 Prof. Okamura delivered an Invited Lecture at the 36th International Conference on Solution Chemistry, held in Xining, China. Her talk was entitled ’Real-Time in-Situ NMR of Biologically Relevant Reactions in Peptide Solution: Spontaneous Peptide Bond Cleavage of Aspartyl Isomers and Preaggregation of Amyloid-β Fragments’.

URL: http://icsc2019.csp.escience.cn/


 In this conference, Dr. Aki also gave a poster presentation entitled ’The Kinetics of Amino Acid Isomerization in Amyloid Beta Fragments Quantified by Real-Time 1H-NMR’, and selected as one of the Top 5 Poster Winners (Excellent).

URL:http://icsc2019.csp.escience.cn/dct/page/70007

In-cell NMR was realized to monitor non-endocytic cell membrane translocation of octaarginine in real time. (April15, 2017)

 Y. Takechi-Haraya, K. Aki, Y. Tohyama, Y. Harano, T. Kawakami, H. Saito, E. Okamura,, Pharmaceuticals, 10, 42 (2017)

Dr. Aki and Prof. Okamura observed spontaneous peptide bond cleavage in lensα-crystallin fragment by real-time NMR in situ. (February15, 2016)

 Dr. Aki and Prof. Okamura performed real-time NMR observation of spontaneous peptide bond cleavage in lens α-crystallin fragment, to show less reactivity of D-β-aspartic acid to allow abnormal accumulation in aged lens. (K. Aki, E. Okamura, Sci, Rep. 6, 21594 (2016))

Professor Emiko Okamura was awarded the 2013 Research Grant from Hyogo Science and Technology Association. (May 27, 2013)

 Dr. Emiko Okamura was awarded the 2013 Research Grant from Hyogo Science and Technology Association. This time the grant is for her research project "The Quantitative In-Cell NMR Observation of Drug Transport into Living Cells to Establish its Prediction Model".

"Slow Tumbling but Large Protrusion of Phospholipids in the Cell Sized Giant Vesicle"

 Y. Takechi, H. Saito, E. Okamura, Chem. Phys. Lett., 570, 136-140 (2013).

"Lateral Diffusion of Lipids Separated from Rotational and Translational Diffusion of a Fluid Large Unilamellar Vesicle"

 N. Yoshii, T. Emoto, E. Okamura, Colloids Surf. B: Biointerfaces, 106, 22-27 (2013).

Profs. Yoshii and Okamura received the 11th Oleoscience Editor's Award. (October 3, 2012)

 Profs. Yoshii and Okamura received the 11th Oleoscience Editor's Award from the Japan Oil Chemists' Society. The award was for an article entitled,

 "Mobility of Drugs in Lipid Membranes by NMR",
 by N. Yoshii and E. Okamura, in Oleoscience, Vol.11, No.6, pp.213~220 (2011).

"Kinetics of binding and diffusivity of leucine-enkephalin in large unilamellar vesicle by pulsed-field-gradient 1H NMR in situ"

 Noriyuki Yoshii, Tomomi Emoto, and Emiko Okamura, BIOPHYSICS, 7, 105-111(2011).

"Binding of Hydrophobic Fluorinated Bisphenol A to Large Unilamellar Vesicles of Egg Phosphatidylcholine"

 Noriyuki Yoshii and Emiko Okamura, J. Phys. Chem. B, 115, 11074-11080 (2011)

Professor Emiko Okamura was selected as a member of a project
"Grant-in-Aid for Scientific Research on Innovative Areas"
by MEXT Japan, entitled Molecular Science of Fluctuations toward Biological Functions. (July 27, 2009)

 Dr. Emiko Okamura was selected as a member of a project "Grant-in-Aid for Scientific Research on Innovative Areas" by MEXT Japan, entitled Molecular Science of Fluctuations toward Biological Functions(http://kuchem.kyoto-u.ac.jp/hikari/yuragi/) The grant is for her research "Multinuclear dynamic NMR of drug transport relating to the fluctuation of biomembranes".

"Kinetics of Membrane Binding and Dissociation of 5-Fluorouracil by Pulsed Field Gradient 19F NMR"

 (N. Yoshii and E. Okamura, Chem. Phys. Lett. 474, 357-361 (2009))

Professor Emiko Okamura was awarded the 2008 Shiseido Female Researcher Science Grant.

 Dr. Emiko Okamura was awarded the 2008 Shiseido Female Researcer Science Grant. The grant, established by Shiseido Co. Ltd., is a program to help foster the development of leading female researchers in scientific and technological fields by supporting the research activities of women majoring in the natural sciences. This time the grant is for her research project "In-cell NMR spectroscopy of drugs: noninvasive detection and transport mechanism".

"Drug Binding and Mobility in Membrane in situ by Multinuclear, Dynamic NMR"

 (E. Okamura and N. Yoshii, J. Chem. Phys. 129, 215102 (2008))

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